Pharmaceutical industry: Process additives such as CIP cleaners and disinfectants for hygienic plant cleaning and process reliability
Reliable process additives for the highest quality standards in the chemical and pharmaceutical industry

ALMA AQUA process additives

Particularly strict quality and process requirements apply in the chemical and pharmaceutical industries. Cooling water, boiler systems, membrane systems and waste water treatment stages must not only be operated stably and efficiently, but also with absolute reliability - as any malfunction can jeopardize the production, quality or approvability of the products.

With ALMA AQUA process additives, operators in chemical and pharmaceutical companies safeguard their plants in the long term. Our additives are formulated to take into account complex process conditions, changing raw water qualities and regulatory requirements in equal measure.
Reliable compliance with regulatory requirements (GMP, FDA, EMA, VDI, DIN)
Stable production processes thanks to clear and deposit-free cycles
Long-term operational reliability - thanks to protection against corrosion, scaling and biofouling
Reduced operating costs - thanks to more efficient dosing and optimized service life
Consistent wastewater quality - even with fluctuating loads
Whether cooling water, boiler systems, membrane systems or waste water treatment - we have the optimum solution for maximum operational safety and product quality.

We ensure the operational safety of your water-bearing systems in the chemical and pharmaceutical industries!

Frank Kuntze

Sales Manager Water and Process Additives

ALMA AQUA solutions for the chemical and pharmaceutical industry

ALMA AQUA boiler

Oxygen binders, alkalizing agents, hardness stabilizers and defoamers for trouble-free and long-lasting operation of boiler systems and steam boiler systems.

ALMA AQUA Mem

Antiscalant, membrane cleaner (acidic, alkaline, oxidative) and cleaning booster for lasting protection and maximum performance of membrane systems.

ALMA AQUA cooling water

Corrosion inhibitors, hardness stabilizers, dispersants, bioinhibitors and biocides for safe, legionella-free evaporative cooling systems & cooling circuits.

ALMA AQUA Waste water

Precipitants, coagulants, flocculants, trace substances and sludge conditioning agents for stable processes and safe discharge values.

Proof of Performance - Our references

Practical benefits for operators

With ALMA AQUA process additives you achieve:
Constant system performance - even with changing raw water quality
Energy savings thanks to clean heat exchanger surfaces
Safe compliance with international guidelines (GMP, FDA, EMA)
Reduced operating costs thanks to optimized dosing
Reliable compliance with all limit values in wastewater treatment
OEM and private label solutions available
Laboratory tests for water treatment plants

Service & technology - everything from a single source

We support you throughout the entire product life cycle:

Advice & system recording

Laboratory and practical tests

Online monitoring & software solutions

Integrated dosing and control technology

Automated additive replenishment

Evaluation & reporting

Formulations & compatibility

Available in different formulations - liquid, emulsion or powder, depending on dosing technology and system requirements
Compliant with regulatory requirements for chemical and pharmaceutical applications (incl. GMP audits and FDA standards)
Compatible with all common system types - open and closed cooling circuits, evaporative coolers, steam boilers, membrane systems (RO, NF), biological and chemical-physical waste water systems
Long-term stability in storage and application - consistent effectiveness even with longer dosing breaks or seasonally varying operation

OEM & private label solutions

Exclusive recipes or standard products
Filling & labeling according to customer design
Accompanying documentation & application recommendation
Perfect for plant manufacturers, OEMs, wholesalers and international distributors
Technical support & system monitoring

FAQ

Our additives are specially formulated for regulated industries. Each batch is supplied with full documentation and certificates of analysis so that operators can prove auditability according to GMP or FDA at any time. Additionally we offer:

  • Traceability via batch numbers and laboratory certificates

  • Digital reporting system for seamless documentation of dosing, monitoring and system parameters

  • Validated dosing strategies that comply with strict production specifications
    This means that chemical and pharmaceutical companies can not only safeguard their processes, but also have access to complete data in the event of an audit.

Cooling water systems in the chemical and pharmaceutical industries are often hygiene-critical and must be operated continuously and reliably. With our additives, operators achieve:

  • Legionella-free and hygienically safe systems thanks to highly effective biocides and bioinhibitors

  • Clean heat exchanger surfaces thanks to hardness stabilizers and dispersants → Lower energy consumption

  • Long-term corrosion protection for metallic system parts → Less downtime due to leaks

  • Stable processes even at high temperatures, changing loads or aggressive raw water qualities

The result: predictable operational reliability, reduced energy costs and a longer service life for the systems.

Membrane systems (e.g. reverse osmosis) are often critical systems in the pharmaceutical industry, as they are used to produce process or ultrapure water. Even the smallest deposits can jeopardize product quality.
Our additives offer clear added value here:

  • Antiscalants prevent deposits caused by hardeners, sulphates and silicates

  • Special cleaning agents dissolve protein, biofilm and organic residues that occur in pharmaceutical processes

  • Cleaning boosters shorten CIP cycles and minimize downtimes
    Practical example: By combining antiscalants and cleaning boosters, a pharmaceutical company was able to extend cleaning intervals from 4 to 7 weeks, resulting in considerable savings in operating costs.

In pharmaceutical plants, any unplanned downtime jeopardizes production safety, batch validation and delivery capability. Boiler systems (steam for sterile processes, clean rooms, autoclaves) and cooling water systems (air conditioning, reactor cooling, process water) are particularly critical.

Typical risks:

  • Corrosion in boiler and cooling circuits → Leaks, contamination

  • Scaling in heat exchangers → Loss of performance, waste of energy

  • Biofouling → hygienic risk, validation problems (e.g. in cooling towers with product proximity)

ALMA AQUA process additives significantly reduce these risks:

  • Oxygen binders and corrosion inhibitors prevent material damage in boilers, thereby avoiding downtimes caused by leaks.

  • Hardness stabilizers and antiscalants keep heat exchangers free of deposits, ensure constant energy efficiency and prevent validation deviations in energy/temperature profiles.

  • Biocides and bioinhibitors control microbial growth in cooling water systems, which is particularly important in order to comply with hygienic GMP requirements.

In addition, we supply complete batch documentation and monitoring reports that can be used directly as evidence in audits (GMP, FDA, EMA). This not only prevents technical failures, but also strengthens the regulatory safety of operations.

Wastewater from the chemical and pharmaceutical industries is among the most complex of all. It is often contaminated discontinuously (e.g. by batch processes) and contains mixtures of organic residues, solvents, salts, heavy metals and nutrient imbalances. Typical problems:

  • Highly fluctuating COD/TOC values → Overloading of biological stages

  • Low biodegradability (high proportion of poorly biodegradable substances)

  • Impurities such as surfactants or emulsions that impair flocculation and sludge stability

  • High disposal costs due to poorly dewaterable sludge

ALMA AQUA process additives specifically address these points:

  • Precipitants (e.g. iron or aluminum salts) remove phosphates, metals and colloidal compounds that would otherwise lead to unstable discharge values.

  • Flocculants with precisely matched charge density ensure that even the finest particles are combined to form large, stable flocs - a prerequisite for reliable separation.

  • Special sludge conditioning agents improve dewaterability → higher dry matter content, lower disposal costs.

  • Trace substances and nutrient doses stabilize the biological residual stage by achieving an optimal C:N:P ratio.

The key in the chemical and pharmaceutical industry lies in a dynamic, adaptive additive strategy that compensates for load fluctuations. With our jar tests, pilot tests and online monitoring, we ensure that the wastewater quality remains reliably within the standard range - even with complex and changing loads.

In the chemical and pharmaceutical industries, energy and operating costs often account for a large proportion of total costs. Cooling water and boiler systems in particular are key consumers here. Even small deposits (1 mm of limescale or milkstone) can increase energy consumption by 10-15 %.

ALMA AQUA process additives specifically counteract this effect:

  • Hardness stabilizers and antiscalants prevent crystal growth and keep heat exchanger surfaces clean.

  • Corrosion inhibitors ensure a smooth surface without the formation of deposits caused by corrosion products.

  • Defoamers stabilize boiler operation and prevent uneven steam formation.

By using these additives, operators in pharmaceutical industry projects have been able to stabilize their heat exchanger performance, increase energy efficiency and reduce CO₂ emissions. The added benefit: The measures can be measured immediately - by monitoring the approach temperature, efficiency or fuel consumption.

Pharmaceutical plants often use high-pressure boiler systems for steam generation - whether for sterilization, autoclaves or reactors. These systems often run 24/7 and are extremely sensitive to deposits and corrosion. Even minor faults can cause production stoppages and validation problems.

The conditioning strategy must therefore:

  • Eliminate oxygen (oxygen binder) to prevent pitting and stress corrosion cracking

  • Stabilize pH (alkalizing agent) to keep pipes and boiler walls in the optimum range

  • Check hardness formers (hardness stabilizers, antiscalants) to prevent deposits on heating surfaces

  • Ensure steam cleanliness (defoamer) to prevent foaming and product contamination

ALMA AQUA boiler additives are formulated precisely for these requirements and can be coupled with online monitoring so that operators receive real-time feedback on conductivity, pH and oxygen content. This not only maximizes operational safety, but also ensures auditability in GMP environments.

Need technical advice? Inquire now!

Frank Kuntze

Sales Manager Water and Process Additives